单项选择题

A nephrologist is educating her patients who has chronic kidney failure secondary to diabetes about how to evaluate the degree of kidney failure progression.She tells her patient that glomerular filtration rate () can be estimated by measuring the levels of some substances. The clearance of which of the following substances is the most accurate estimate for GFR? ()

A.Creatinine
B.Glucose
C.Inulin
D.Paraaminohippurate (PAH)
E.Sodium
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